Podcast episode · 18 November 2025

Sam Vanderpump Champions Life Changing Organ Donation After Liver Disease Diagnosis

Made in Chelsea star Sam Vanderpump opens up about life behind reality TV, the advice his aunt Lisa Vanderpump gave him, and the rare liver disease that…

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106 min

About this conversation

Made in Chelsea star Sam Vanderpump opens up about life behind reality TV, the advice his aunt Lisa Vanderpump gave him, and the rare liver disease that now means he faces a life-saving transplant.

For the first time, Sam reflects on growing up as part of the Vanderpump family, the pressure of living up to his father’s expectations, and the moment he nearly lost his life to sepsis. He also shares how reality TV unexpectedly helped him process trauma, why he’s determined to use his platform to raise awareness for organ donation, and how love and fatherhood have given him new purpose.

Sam shares:

◽ The truth behind the Vanderpump family legacy

Episode summary and show notes supplied by the official We Need To Talk feed.

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Chapters from the official episode notes. Timings may vary when adverts are inserted.

More from the official show notes

◽ What his father’s death taught him about love, pride, and approval

◽ How Lisa Vanderpump became a father figure in his life

◽ The terrifying day he went into organ failure

◽ How Made in Chelsea helped him confront his emotions for the first time

◽ The moment media headlines about his illness broke him

◽ Why he’s now fighting to raise awareness for organ donation and liver disease

◽ The message from his fiancée that left him in tears

Sam Vanderpump. We Need To Talk.

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